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Intraluteal Release of Prostaglandin F2α and E2 During Corpora Lutea Development in the Cow OAK
KOBAYASHI, Shu-ichi; ACOSTA, Tomas J.; HAYASHI, Kanako; BERISHA, Bajram; OZAWA, Takahiro; OHTANI, Masayuki; SCHAMS, Dieter; MIYAMOTO, Akio; 宮本, 明夫.
It is well known that prostaglandin (PG) F2α and PGE2 are actively produced by bovine early corpus luteum (CL) at higher levels than in the CL of later stages. However, there is no in vivo information about the local secretion of PGs within bovine developing CL so far. Thus, the objective of the present study was to determine in detail the real-time changes in PGF2α and PGE2 secretion within developing CL. A microdialysis system (MDS) was surgically implanted into the newly formed CL of 6 cows on Day 3 after GnRH administration (about 1.5 days after ovulation) to induce superovulation following FSH treatment. Both PGF2α and PGE2 release were high during the first 24 h within developing CL but decreased thereafter. These profiles were well reflected in the...
Palavras-chave: PGF2α; PGE2; Developing CL; Cow; In vivo.
Ano: 2002 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2974
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Patologías uterinas y fertilidad de vacas lecheras tratadas con dos inyecciones de PGF2α en las primeras 48 horas posparto Veterinaria México
Ortega Ornelas,Adriana; López Ordaz,Reyes; Mapes,Gabriela; Ortiz González,Óscar; Hernández Cerón,Joel.
En el presente estudio se probó si la administración de dos inyecciones de PGF2α en las primeras 48 h posparto, disminuye la incidencia de patologías uterinas y favorece la fertilidad en vacas lecheras. Se utilizaron 445 vacas Holstein de diferente número de parto con una producción promedio de 10 100 kg de leche por lactancia. El día del parto las vacas se asignaron a dos grupos balanceando la proporción de vacas con diferente número de parto: grupo PGF2α (n = 180), estas vacas recibieron una inyección de 500 mcg de cloprostenol sódico, vía intramuscular, dentro de las primeras 12 h posparto, y una segunda inyección 48 h después. El grupo testigo (n = 265) no recibió PGF2α. Todas las vacas tuvieron una revisión vía rectal el día 7 posparto, se registró el...
Tipo: Info:eu-repo/semantics/article Palavras-chave: PGF2α; Fertilidad; Vacas lecheras.
Ano: 2012 URL: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0301-50922012000300005
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Prostaglandin F2α Increases Lipoprotein Utilization for Progesterone in Bovine Early Corpora Lutea In Vitro OAK
KOBAYASHI, Shu-ichi; MIYAMOTO, Akio; 宮本, 明夫.
Luteal cells utilize lipoproteins (LIPs) for progesterone (P) synthesis. A luteolysin prostaglandin F2α (PGF 2α) has shown to prevent the LIPs utilization for steroidogenesis in bovine midcycle luteal cells. However, a luteolytic injection of PGF2α before Day 5 (Day 0=estrus) can not induce the regression of the corpus luteum (CL). This suggests that the intraluteal mechanism of PGF2 α action on the LIPs utilization in early CL is different from that of the mid luteal stage. Thus, this study aimed to investigate the interaction between PGF2 α and LIPs on the secretion of P and oxytocin (OT) from bovine early CL. An in vitro microdialysis system (MDS) was used as a model. Each bovine early CL (Days 3-4) was implanted with the MDS, and maintained in an organ...
Palavras-chave: PGF2α; Lipoproteins; Early CL; Cow.
Ano: 2000 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2972
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退行しない黄体の作出に向けた分子生理学的研究 OAK
宮本, 明夫; MIYAMOTO, AKIO.
2007年度~2009年度科学研究費補助金基盤研究(B) 研究成果報告書19380154
Palavras-chave: 黄体; 退行; PGF2α; 血管機能; データベース; ウシ.
Ano: 2010 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2760
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